Events

The topic of our round-table workshop May 29, 2025 will be i-HMBC Methodology: Applications and Enhancements In 2023, researchers at Merck & Co. Inc. reported the i-HMBC methodology which allows differentiation of 2JCH from 3+nJCH correlations based on comparative analysis of two-bond 2Δ1H(13/12C) and three-bond 3Δ1H(13/12C) isotope shifts. This innovation obviates the sensitivity challenges associated with the[...]

Despite the power and wide acceptance of 2D 1H–13C-correlative NMR, HSQC for example, spectra may still look like nothing more than Rorschach tests to researchers unfamiliar with NMR. To this day, researchers seem amazed at how conclusively and unambiguously and we can identify peaks for individual structures in HSQC spectra[...]

In recent years, it has been discovered that heterogeneous diseases such as cardiovascular diseases, diabetes, hepatitis and cancer may be attacked effectively by developing specific treatment plans that are generally referred to as personalized treatments. This new approach in medicine involves using novel methodology as a bridge between diagnostic and[...]

"Post-translational modifications (PTMs) are key regulators of many cellular processes, leading to a variety of cellular events. While some PTMs such as phosphorylation are extensively studied, proline hydroxylation, an oxygen-dependent and rare PTM, remains poorly understood due to a lack of site-specific detection methods. Hypoxia-Inducible Factor (HIF) proteins are a[...]

NMR is one of the best analytical tools for the quantification of samples and identification of unknown molecules. It is also a near-universal detector if the concentration of the analyte is sufficient. Given these great strengths, why is NMR metabolomics lagging LC-MS metabolomics? My answer is that both quantification and[...]

The topic of our round-table workshop on February 26, 2026, will be Automated Structure Verification: Balancing Speed and Accuracy in NMR Analysis. Advances in NMR instruments and methods now let scientists collect large amounts of 1D and 2D data very quickly. This leaves processing and interpreting that data as the[...]

Pure shift spectra (1D or 2D) by homonuclear BB decoupling are typically accomplished by selective inversion of passive spins midway between dwell points or chunks of dwell points during acquisition and the magnetization is sampled when all the multiplet vector trajectories are at or very near their chemical shift trajectory.[...]

Mark your calendar for April 11 th for the 2026 IVAN user meeting. This year our meeting will be a symposium devoted entirely to the topic “Environmental NMR”. The symposium will be in-person in the IVAN suite, Oak Shelter, at Asilomar, and it will also be broadcast live-stream on Zoom.[...]

Join us in the suite each evening for the IVAN Hour, Monday through Wednesday. We have three great talks! Monday Night - April 13, 2026 @ 8:00PM - “The History of NMR in South America” - Tito J. Bonagamba, IFSC-USP, Sonia de Menezes, Petrobras (Ret.) Tuesday Night - April 14,[...]

Here is a list of proposed IVAN Users Group Research Workshops. These are all still in the planning stages and more information will be provided as the meetings get confirmed. Please check back regularly for updates. AI in NMR - Date and time are being finalized for this meeting currently[...]

The topic of our round-table workshop on Thursday September 24, 2026 will be AI and Large Language Models for NMR Spectral Artificial intelligence and large language models are developing rapidly and are increasingly being applied to chemistry-related problems, including NMR spectral prediction, interpretation, and structure elucidation. This workshop will examine the[...]